Trichomycin is an antibiotic obtained from cultures of Streptomyces hachi- joensis. It was isolated for the first time in 1952 by Hosoya et al. who discov- ered the microorganism in a soil sample from a Japanese island. Its chemical structure is not yet completely known but according to Hattori et al. the molecule is a conjugated heptaene. As a powder it is stable but in solution it progressively loses activity. In vitro and in vivo experiments demonstrated that trichomycin is highly effective against Candida albicans and other yeasts and against Trichomonas vaginalis . It is also active against some pathogenic fungi and several protozoan parasites, especially flagellata and amoeba.
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